Product Name: CompoZr® Knockout ZFN Kit, miRNA TargetNR-030217
Product Type: Chemical
CAS NO: 59277-89-3
NCBI accession no.: NR_030217
Shipped in: dry ice
Storage temp.: −70°C
General description: CompoZr Knockout ZFNs create a targeted double strand break at a specific DNA sequence within the genome. Through the cellular process of non-homologous end joining, this double strand break can result in frequent deletions and/or insertions at the target locus which disrupt microRNA hairpin formation and therefore create a functional microRNA knockout.
Legal Information: All Zinc Finger Nucleases are sold under license from Sangamo Biosciences. For a copy of the Label License provided with purchase of CompoZr ZFNs, please visit the ZFN Label License page.
Legal Information: CompoZr is a registered trademark of Sigma-Aldrich Co. LLC
Physical form: CompoZr Knockout ZFNs are provided as two plasmids encoding for the gene specific zinc finger nuclease and 10 aliquots of mRNA encoding for the ZFN. Also included in the kit are custom-designed primers, that allow for determination of the rate of mutation and for screening of individual clones that have the desired mutational event, and positive control DNA that has been modified using the CompoZr Knockout ZFN.
RIDADR： NONH for all modes of transport
Storage Temp.:−70°C
UNSPSC: 12352200