The synthesis of D-isoascorbyl palmitate via lipase-catalyzed esterification offers a green and efficient alternative to chemical methods, but its industrial application has been hindered by prolonged reaction times and suboptimal…
The oncogenic potential of Merkel cell polyomavirus (MCV) is tightly linked to the structural integrity of its large T antigen (LT). While the full-length MCV LT protein possesses multifunctional domains…
Brugada syndrome, a rare inherited arrhythmia disorder associated with sudden cardiac death, has long been considered a monogenic condition primarily caused by mutations in SCN5A. However, recent evidence suggests a…
To assess the performance of parametric maximum likelihood estimation (MLE) under right truncation, a comprehensive simulation study was conducted across three parametric distributions: exponential, Weibull, and log-logistic. These distributions were…
The human EGF repeat-specific O-GlcNAc transferase EOGT is a conserved enzyme responsible for modifying epidermal growth factor (EGF) repeats in secreted glycoproteins. In this study, we demonstrate that a splice…