Haemorrhage Glasgow Coma Scale score on scene, median (IQR) Surgical proceduresHaemorrhage Glasgow Coma Scale score

Haemorrhage Glasgow Coma Scale score on scene, median (IQR) Surgical procedures
Haemorrhage Glasgow Coma Scale score on scene, median (IQR) Surgical procedures, N ( ) Haematomacontusion evacuation Extraventricular drainage Transfusion, median (IQR) Red blood cells, units Fresh frozen ALK1 Compound plasma, units Norepinephrine infusion on admission, N ( ) Fluid infusion just before inclusion, median (IQR) Crystalloids (NaCl 0.9 ), ml Akt2 site Colloids, ml Time from brain injury to inclusion (hours) median (IQR) Biological status on inclusion Hyperchloraemic acidosis, N ( ) Osmolarity (mOsmL), median (IQR) Natraemia (mmolL), median (IQR) Chloraemia (mmolL), median (IQR) Kalemia (mmolL), median (IQR) Ionized calcaemia (mmolL), median (IQR) Magnesemia (mmolL), median (IQR) Phosphoremia (mmolL), median (IQR) Lactataemia (mmolL), median (IQR) Azotaemia (molL), median (IQR) Albuminaemia (gL), median (IQR) pH, median (IQR) SID (mmolL), median (IQR)aIntention-to-treat population Saline (N = 21) 51 (25 – 68) 15 (71) 19 (90) two (ten) eight (seven – 9) 9 (43) 2 (10) 4 (19) 3 (14) eight (38) 1000 (500 -1000) 0 (0 – 500) five (three – seven) four (19) 303 (295 – 319) 140 (138-142) 106 (104 – 110) 3.six (3.four – three.9) one.10 (one.07 – one.14) 0.86 (0.72 – 0.95) 0.86 (0.67 – one.07) 1.four (one.one – 2.one) 66 (56-73) 36 (32 – 41) 7.38 (7.33 – seven.44) 39 (35 – 42) Balanced (N = 20) 49 (26 – 75) 17 (85) 18 (90) two (10) seven (6 – 9) four (twenty) two (ten) three (15) 0 7 (35) one thousand (500 – 1500) 0 (0 – 500) 5 (4 – 12) two (ten) 302 (296 – 319) 139 (137-141) 106 (101 – 107) three.7 (3.5 – four.one) 1.11 (one.07 – 1.18) 0.81 (0.75 – 0.88) 0.85 (0.74 – one.14) 1.7 (one.1 – 2.7) 67 (58-71) 37 (34 – 39) 7.39 (seven.32 – seven.45) 39 (39 – 41)TBI sufferers Saline (N = 18) 47 (28-57) 13 (72) 7 (6-8) eight (44) 0 four (22) three (17) 7 (39) 500 (500 -1000) 0 (0 – 500) 4 (3-6) four (22) 306 (299-328) 140 (138-141) 106 (104-111) 3.seven (three.4-3.9) 1.ten (one.08-1.12) 0.82 (0.76-0.92) 0.88 (0.70-1.ten) one.5 (1.2-2.two) 65 (56-72) 34 (32-41) 7.36 (seven.31-7.41) forty (37-41) Balanced (N = 18) 49 (27-77) 16 (89) seven (6-8) four (22) 0 3 (17) 0 seven (39) 1000 (500 -1500) 0 (0 – 500) five (4-6) two (11) 306 (300-319) 139 (137-141) 106 (100-107) three.7 (three.5-4.1) 1.eleven (1.06-1.18) 0.83 (0.73-0.92) 0.82 (0.73-1.13) two.0 (1.1-2.7) 67 (60-71) 36 (34-39) seven.39 (seven.31-7.45) 39 (37-41)IQR: interquartile range; TBI: traumatic brain damage; Powerful Ion Big difference (SID) = (Na K Ca Mg) – (Cl lactate).Table three Fluid administration inside of the initial 48 hoursMedian (IQR) Saline group (N = 20) Na administration (mmol) Cl administration (mmol) Crystalloids (ml) H0 to H48 H0 to H48 H0 to H6 H6 to H24 H24 to H48 H0 to H48 Hydroxyethyl starch solutions (ml) H0 to H6 H6 to H24 H24 to H48 H0 to H48 918 (689 to one,148) 918 (689 to one,148) two,000 (one,000 to 2,000) 2,000 (1,500 to 2,000) 2,000 (one,500 to two,000) 5,000 (four,500 to six,000) 0 (0 to 500) 0 (0 to 500) 0 (0 to 0) 500 (0 to one,500) Balanced group (N = 20) 840 (630 to 1,050) 744 (572 to 952) 1,000 (500 to 2,000) one,500 (one,500 to two,000) two,000 (1,500 to 2,000) five,000 (4,000 to 6,000) 0 (0 to 500) 0 (0 to 500) 500 (0 to one,000) 1,000 (500 to 1,500) P-value 0.228 0.014 0.255 0.530 0.755 0.448 0.613 0.563 0.060 0.Roquilly et al. Vital Care 2013, 17:R77 http:ccforumcontent172RPage seven ofFigure two Kaplan-Meier curves for hyperchloraemic acidosis. Hyperchloraemic acidosis was defined because the association of hyperchloraemia (108 mmolL) with robust ion variation (SID) (40 mmolL). SID = (Na K Ca Mg) – (Cl lactate). Na; sodium, K; potassium; Ca: calcium; Mg: magnesium; Cl: chloride.Roquilly et al. Important Care 2013, 17:R77 http:ccforumcontent172RPage 8 ofFigure three Time course of acid-base standing in the.