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A later time, P2, TrkA-positive fibers in wild-type mice have invaded the spinal cord and are absolutely restricted to their target fields inside the dorsal laminae (Figure 3J, n = 7). In contrast, in npn-1Sema- mice, some axons have been observed outdoors of their standard termination zones, traveling along the midline and into the medial-ventral spinal cord (Figure 3K, n = 7). Comparable aberrant Serpinb3b Proteins Purity & Documentation projections had been reported in sema3A null mice (Behar et al., 1996). As a result, Sema3A signaling by way of Npn-1 is certainly necessary for guiding the central projections of a subset of TrkA-positive axons of Share this post on:

Author: calcimimeticagent