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Unol 23: 375384. 9. Schwartz R, Engel I, Fallahi-Sichani M, Petrie HT, Murre C Gene expression patterns define novel roles for E47 in cell cycle progression, cytokinemediated signaling, and T lineage improvement. Proc Natl Acad Sci U S A 103: 99769981. 10. Slattery C, McMorrow T, Ryan MP Overexpression of E2A proteins induces epithelial-mesenchymal transition in human renal proximal tubular epithelial cells suggesting a possible part in renal fibrosis. FEBS Lett 580: 4021 4030. 11. Seidel MG, Examine E2A-HLF usurps manage of evolutionarily conserved survival pathways. Oncogene 20: 57185725. 12. Aspland SE, Bendall HH, Murre C The role of E2A-PBX1 in leukemogenesis. Oncogene 20: 57085717. 13. LeBrun DP E2A Eliglustat chemical information standard helix-loop-helix transcription variables in human leukemia. Front Biosci eight:s206222. 14. Mo ML, Chen Z, Zhou HM, Li H, Hirata T, et al. Detection of E2APBX1 fusion transcripts in human non-small-cell lung cancer. J Exp Clin Cancer Res doi: 10.1186/1756 -9966-32-29. 15. Slyper M, Shahar A, Bar-Ziv A, Granit RZ, Hamburger T, et al. Manage of breast cancer growth and initiation by the stem cell-associated transcription aspect TCF3. Cancer Res 72: 56135624. 16. Hwang-Verslues WW, Chang PH, Wei Pc, Yang CY, Huang CK, et al. miR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of Homatropine methobromide site E-cadherin and REDD1. Oncogene 30: 24632474. 17. Patel D, Chaudhary J Improved expression of bHLH transcription element E2A in prostate cancer promotes proliferation and confers resistance to doxorubicin induced apoptosis. Biochem Biophys Res Commun 422: 146151. 18. Engel I, Murre C Ectopic expression of E47 or E12 promotes the death of E2A-deficient lymphomas. Proc Natl Acad Sci U S A 96: 9961001. 19. Lietz A, Janz M, Sigvardsson M, Jundt F, Dorken B, et al. Loss of bHLH transcription aspect E2A activity in main effusion lymphoma confers resistance to apoptosis. Br J Haematol 137: 342348. 20. Liu TY, Chen SU, Kuo SH, Cheng AL, Lin CW E2A-positive gastric MALT lymphoma has weaker plasmacytoid infiltrates and stronger expression with the memory B-cell-associated miR-223: attainable correlation with stage and treatment response. Mod Pathol 23: 15071517. 21. Mao Z, Sun J, Feng B, Ma J, Zang L, et al. The Metastasis Suppressor, Nmyc Downregulated Gene 1, Is actually a Prognostic Biomarker for Human Colorectal Cancer. PLoS One particular doi: 10.1371/journal.pone.0068206. 22. Dong TT, Zhou HM, Wang LL, Feng B, Lv B, et al. Salinomycin selectively targets `CD133+’ cell subpopulations and decreases malignant traits in colorectal cancer lines. Ann Surg Oncol 18: 17971804. 23. Zhao F, Vilardi A, Neely RJ, Choi JK Promotion of Cell Cycle Progression by Basic Helix-Loop-Helix E2A. Molecular and Cellular Biology 21: 63466357. 24. Prabhu S, Ignatova A, Park ST, Sun XH Regulation from the expression of cyclin-dependent kinase inhibitor p21 by E2A and Id proteins. Mol Cell Biol 17: 58885896. 25. Farazi TA, Spitzer JI, Morozov P, Tuschl T miRNAs in human cancer. J Pathol 223: 102115. 26. Zhang Y, He X, Liu Y, Ye Y, Zhang H, et al. microRNA-320a inhibits tumor invasion by targeting neuropilin 1 and is related to liver metastasis in colorectal cancer. Oncol Rep 27: 685694. 27. Siegel R, Naishadham D, Jemal A Cancer statistics, 2013. CA Cancer J Clin 63: 1130. 28. Fearon ER Molecular genetics of colorectal cancer. Annu Rev Pathol six: 479507. 29. Walther A, Johnstone E, Swanton C, Midgley R, Tomlinson I, et al. Genetic pro.Unol 23: 375384. 9. Schwartz R, Engel I, Fallahi-Sichani M, Petrie HT, Murre C Gene expression patterns define novel roles for E47 in cell cycle progression, cytokinemediated signaling, and T lineage development. Proc Natl Acad Sci U S A 103: 99769981. ten. Slattery C, McMorrow T, Ryan MP Overexpression of E2A proteins induces epithelial-mesenchymal transition in human renal proximal tubular epithelial cells suggesting a prospective function in renal fibrosis. FEBS Lett 580: 4021 4030. 11. Seidel MG, Take a look at E2A-HLF usurps handle of evolutionarily conserved survival pathways. Oncogene 20: 57185725. 12. Aspland SE, Bendall HH, Murre C The role of E2A-PBX1 in leukemogenesis. Oncogene 20: 57085717. 13. LeBrun DP E2A basic helix-loop-helix transcription components in human leukemia. Front Biosci 8:s206222. 14. Mo ML, Chen Z, Zhou HM, Li H, Hirata T, et al. Detection of E2APBX1 fusion transcripts in human non-small-cell lung cancer. J Exp Clin Cancer Res doi: ten.1186/1756 -9966-32-29. 15. Slyper M, Shahar A, Bar-Ziv A, Granit RZ, Hamburger T, et al. Manage of breast cancer development and initiation by the stem cell-associated transcription factor TCF3. Cancer Res 72: 56135624. 16. Hwang-Verslues WW, Chang PH, Wei Computer, Yang CY, Huang CK, et al. miR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance by means of downregulation of E-cadherin and REDD1. Oncogene 30: 24632474. 17. Patel D, Chaudhary J Improved expression of bHLH transcription factor E2A in prostate cancer promotes proliferation and confers resistance to doxorubicin induced apoptosis. Biochem Biophys Res Commun 422: 146151. 18. Engel I, Murre C Ectopic expression of E47 or E12 promotes the death of E2A-deficient lymphomas. Proc Natl Acad Sci U S A 96: 9961001. 19. Lietz A, Janz M, Sigvardsson M, Jundt F, Dorken B, et al. Loss of bHLH transcription issue E2A activity in main effusion lymphoma confers resistance to apoptosis. Br J Haematol 137: 342348. 20. Liu TY, Chen SU, Kuo SH, Cheng AL, Lin CW E2A-positive gastric MALT lymphoma has weaker plasmacytoid infiltrates and stronger expression with the memory B-cell-associated miR-223: feasible correlation with stage and treatment response. Mod Pathol 23: 15071517. 21. Mao Z, Sun J, Feng B, Ma J, Zang L, et al. The Metastasis Suppressor, Nmyc Downregulated Gene 1, Is a Prognostic Biomarker for Human Colorectal Cancer. PLoS 1 doi: ten.1371/journal.pone.0068206. 22. Dong TT, Zhou HM, Wang LL, Feng B, Lv B, et al. Salinomycin selectively targets `CD133+’ cell subpopulations and decreases malignant traits in colorectal cancer lines. Ann Surg Oncol 18: 17971804. 23. Zhao F, Vilardi A, Neely RJ, Choi JK Promotion of Cell Cycle Progression by Standard Helix-Loop-Helix E2A. Molecular and Cellular Biology 21: 63466357. 24. Prabhu S, Ignatova A, Park ST, Sun XH Regulation from the expression of cyclin-dependent kinase inhibitor p21 by E2A and Id proteins. Mol Cell Biol 17: 58885896. 25. Farazi TA, Spitzer JI, Morozov P, Tuschl T miRNAs in human cancer. J Pathol 223: 102115. 26. Zhang Y, He X, Liu Y, Ye Y, Zhang H, et al. microRNA-320a inhibits tumor invasion by targeting neuropilin 1 and is associated with liver metastasis in colorectal cancer. Oncol Rep 27: 685694. 27. Siegel R, Naishadham D, Jemal A Cancer statistics, 2013. CA Cancer J Clin 63: 1130. 28. Fearon ER Molecular genetics of colorectal cancer. Annu Rev Pathol 6: 479507. 29. Walther A, Johnstone E, Swanton C, Midgley R, Tomlinson I, et al. Genetic pro.

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