Product Name :
RG 13022
Synonym :
Chemical Name :
CAS NO.:
136831-48-6
Molecular formula :
C16H14N2O2
Molecular Weight:
266.29 g/mol
Classification :
MedChemExpress Products > Research Chemicals > RG 13022
Description:
RG 13022 is a tyrosine kinase inhibitor that blocks the activity of protein tyrosine kinases and prevents the activation of proteins downstream in the cell signaling pathway. RG 13022 has been shown to inhibit cell proliferation, induce apoptosis, and significantly decrease tumor volume in a model system. It also inhibits the growth of subcutaneous tumors in mice by blocking the mitogenic effects of epidermal growth factor receptor (EGFR) and other receptor activities. RG 13022 has demonstrated cytotoxicity against cancer cells lines derived from human carcinoma, including squamous carcinoma.br>RG 13022 is orally bioavailable and has shown no significant toxicity or side effects in animal studies. It can be used for treatment of cancer as well as for prevention of relapse after chemotherapy.br>
Purity :
>98%
Specifications :
10 mM * 1 mL
Price.:
73
Price unit :
$
Inventory :
In stock
Related websites: https://www.medchemexpress.com
525-66-6 Formula 477775-14-7 Biological Activity PMID:28846236 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com
