Al[11,12]. 3. ResultThe bioactive compounds present in the ethanolic extract of leaf of E. serratus had been identified by GC-MS evaluation (Figure 1).RT: 0.00-46.4.2 four.0 three.eight 3.six 3.4 three.2 three.0 two.8 two.six two.4 two.2 2.0 1.eight 1.six 1.4 1.two 1.0 0.8 0.six 0.4 0.2 0.T he identity of your components within the extract wasNL:RT: retention time.p-Menthane-1-thiol 1-Benzylthio-4-methyl-1,3-pentadiene 1-Octadecanol Citronellyl isobutyrate Docosanoic acid, 1,two,3-propanetriyl ester 2-Octyldodecan-1-ol Ricinoleic acid Dotriacontane Hexadecanoic acid, methyl ester 1-Hexadecene Pent-4-enal 9-Nitro-1-nonene 1-(Chloromethyl)-3-methylene-1-cyclobutanol Cyclohexane, ethyl5,6-Epoxy-6-methyl-1,9-decadien-4-one 2-Methylsulfonyl-3,3-diethyloxirane 8-Ethenyloxocan-2-one 1-Dotriacontanol Farnesol N-Benzyl-N-(1-phenylethylidene)amine1-(Pent-1-enyl)cyclopropanolC18H38OC69H98O132 112 180 178 154 466 222C7H14O3S6.73ETIC MS EM-4. DiscussionAmong the identified phytochemicals, the fatty acid esters namely, docosanoic acid, 1,two,3-propanetriyl ester, hexadecanoic acid methyl ester possess the house of antioxidant, hypocholesterolemic, nematicide, pesticide, flavouring agent, lubricant and anti-androgenic activities. The biological activities listed are depending on Dr. Duke’s phytochemical and ethanobotanical databases by Dr. Jim Duke of your Agricultural Investigation Service/USDA. Analogous for the present study, hexadecanoic acid methyl ester was identified in the methanol extract of Spirulina platensis. The ethanolic extract of Mussaenda frondosa was subjected to GC-MS analysis and 20 chemical constituents namely ( – ) -quinic acid, four – (( 1 e ) – three -hydroxy- 1 -propenyl ) – two methoxyphenol, Aryl Hydrocarbon Receptor site naphthalene,decahydro- 2 -methoxy, 1 , two, 3-benzenetriol, hexadecanoic acid ethyl ester, linoleicRelative abundance17.26.68 3.44 3.61 3.78 13.67 three.73 30.95 four.16 23.21 9.99 4.45 35.00 17.95 4.79 29.00 36.91 24.07 13.19 17.67 5.72 34.91 19.38 six.03 0 five ten 15 20 25 3022.41.38 41.52 41.T hirty compounds had been detected inside the ethanolic extract of E. serratus leaf. The active principles with their retention time, molecular formula, molecular weight and concentration ( ) within the ethanol extracts of leaf of E. serratusFigure 1. GC-MS chromatogram of ethanolic extract on the leaf of E. serratus.Geetha DH et al./Asian Pac J Trop Biomed 2013; three(12): 985-acid ethyl ester, oleic acid, etc. had been identified. The compounds farnesol and citronellyl isobutyrate are present within the ethanolic leaf extract of E. serratus. The compound farnesol is definitely an acyclic sesquiterpene alcohol, and it has been recommended to function as a chemopreservative and antitumor agent. It’s also utilised as a deodorant in cosmetic products due to its anti-bacterial activity. T he anti-fungal activity of farnesol has also been reported. Citronellyl isobutyrate is an ester of propanoic acid which is broadly utilised as flavoring agent and is identified to possess insect repellent and antimicrobial properties[18-20]. Our systematic investigation reveals the prospective of E. serratus leaves as a superb supply of bioactive compounds such as fatty acid esters, alcohols, hydrocarbons, aldehydes, alkenes, fatty acids and amides that justify the usage of this plant for its several ailments by standard practitioners. mAChR4 web Further investigation interest in the study of these active bio compounds may perhaps yield nature friendly powerful antioxidant, anti-microbial, anti-inflammatory agents and analgesic agents. Conflict of interest statement We declare that we’ve got no conflict of in.